ANTIDEPRESSANT-LIKE ACTIVITY OF FLOWERS OF TECOMELLA UNDULATA IN MICE SUBJECTED TO CHRONIC UNPREDICTABLE MILD STRESS
نویسندگان
چکیده
منابع مشابه
Behavioral and biochemical evidences for antidepressant-like activity of palmatine in mice subjected to chronic unpredictable mild stress.
BACKGROUND In the present study, antidepressant-like activity of palmatine was evaluated in unstressed and stressed young male Swiss albino mice. METHODS The animals were subjected to unpredictable mild stress daily for 21 successive days to induce depression-like behavior. Palmatine (0.25, 0.5, 1 mg/kg, ip) was administered for 21 successive days to unstressed and stressed mice. The antidepr...
متن کاملAntidepressant-Like Effects of Cordycepin in a Mice Model of Chronic Unpredictable Mild Stress
Cordycepin (3'-deoxyadenosine), a major bioactive component isolated from Cordyceps militaris, has multiple pharmacological activities. This study is attempted to investigate whether cordycepin (COR) possesses beneficial effects on chronic unpredictable mild stress- (CUMS-) induced behavioral deficits (depression-like behaviors) and explore the possible mechanisms. ICR mice were subjected to ch...
متن کاملSocial Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress
BACKGROUND Accumulating epidemiological evidence shows that life event stressors are major vulnerability factors for psychiatric diseases such as major depression. It is also well known that social isolation in male mice results in aggressive behavior. However, it is not known how social isolation-induced aggression affects anxiety and depressive-like behavior in isolated male mice subjected to...
متن کاملAntidepressant-like effects of the fractions of Xiaoyaosan on rat model of chronic unpredictable mild stress.
ETHNOPHARMACOLOGICAL RELEVANCE Xiaoyaosan (XYS), composed of Radix Bupleuri, Radix Angelicae Sinensis, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, Poria, Herba Menthae, Rhizoma Zingiberis Recens and Radix Glycyrrhizae, is a valuable traditional Chinese medicine (TCM) which is used for the treatment of depression in China. In the formula, Radix Bupleuri usually serves as the princip...
متن کاملAntidepressant effects of hydroalcoholic extract of Alpinia officinarum rhizome on chronic unpredictable stress induced depression in BALB/c mice
Background: Alpinia officinarum is an aromatic plant that show some neuroprotective functions in animal models. Objective: This study aimed to evaluate the antidepressant effects of hydroalcoholic extract of A. officinarum rhizome using two behavioral models. Methods: Forty male BALB/c mice were randomized to four groups. All studygroups underwent three weeks of daily chronic unpredictable str...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2019
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2018.v12i1.28981